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Cooling Enhancement

Cooling
Ehancement

Amplifying cooling intensity, extending cooling duration, and broadening sensory coverage for a naturally superior cooling experience.

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Common Sensory Challenge Of Menthol in Beverages

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Short Cooling Duration

Traditional cooling agents lose their cooling effect quickly when exposed to heat or air.
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Hard to Balance Cooling Performance and Taste

Low levels of menthol provide little cooling, while higher levels can cause bitterness, irritation, and a burning sensation.
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Feel Unnatural

Traditional cooling agents deliver a sharp, short-lived cooling effect mainly in the throat, creating an artificial experience with little flavor retention.

Redefining Cooling Perception

< 8°C 8-22°C 22-40°C > 40°C Noxious cold Innocuous cool Innocuous warm Noxious heat TRPC5 TRPV3 TRPV4 TRPM2 TRPM4 TRPV1 TRPM3 TRPM8

Traditional Cooling: Activating Cooling Receptors, but Also Heat Signals

Traditional cooling agents, such as menthol, create cooling sensations primarily by activating the TRPM8 receptor. However, menthol also stimulates heat-sensitive receptors including TRPV3 and TRPM4, which can introduce irritation, burning sensations, and an overall less natural cooling experience.

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EPC's New Understanding of Cooling Perception

Through extensive research on TRP channel interactions, EPC discovered that cooling perception is influenced not only by the strength of cooling signals, but also by the balance between cooling and heat-related pathways.

By reducing interference from heat-sensitive receptors such as TRPV3 and TRPM4 while preserving TRPM8-mediated cooling signals, it is possible to enhance sensitivity to cooling, increase cooling intensity and duration, and minimize irritation and burning sensations.

Because TRPV3 and TRPM4 are widely distributed throughout the oral cavity, throat, and airway, this mechanism also extends cooling sensations across a broader sensory area, delivering a cleaner, more balanced, and longer-lasting cooling experience.

Creating an Extraordinary Cooling Experience

Prolong cooling duration

Cooling Duration (menthol solution, 4% sugar) Intensity (relative value) Time (sec) 0 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 90 95 100 0 1 2 3 4 Menthol + 4% Sugar Menthol + 4% Sugar + 100ppm EPCool+ 007

Enhance the cooling intensity

Relative cooling intensity 0 1 2 3 4 Cooling intensity (relative value) Sample Menthol Menthol + 100ppm EPCool+ 007 Menthol + 4% sucrose Menthol + 4% sucrose + 100ppm EPCool+ 007

Cooling Enhancer: EPCool+™ 007

Expand the cooling perception area

Proven Performance in Real Applications

Enhance Cooling Sensation &
Optimize Menthol Performance
Menthol Ice TeaEnhance Cooling Sensation &
Masking Menthol Off-note
Menthol Tablet Candy
Menthol Ice Tea Sensory Evaluation Coolness onset Overall Liking Bitterness Mint flavor Coolness intensity Coolness duration Control Solution EPC internal test, 8 people

Control: Menthol Ice Tea

Solution: Menthol Ice Tea + 250ppm EPCool +™ 007

  • Accelerate Coolness Onset
  • Prolong Coolness Duration
  • Expand Coolness Area
  • Masking Menthol Bitterness
  • Improve Overall Liking
Menthol Tablet Candy Coolness Time-Intensity 0 20 40 60 80 100 0 50 100 150 Intensity of Coolness Time, sec Control Solution EPC internal test, 8 people

Control: Menthol Candy

Solution: Menthol Candy + 100ppm EPCool +™ 007

  • Accelerate Coolness Onset
  • Prolong Coolness Duration
  • Expand Coolness Area
  • Masking Menthol Bitterness
  • Improve Overall Liking

Suitable for

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Confectionery

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Oral Care Products

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E-cigarettes

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Tea Beverages

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Healthcare
Products